The problem is “how can the use of Questioning Strategy improve students’ reading comprehension?” and “how can the use of Questioning Strategy improve students’ participation?” and the objective of this research referring to the research problem is to find out how the use of Questioning Strategy can improve students’ reading comprehension and students participation. The design of this research is classroom action research. The research subject is XI IPS class consisting of 32 students. The data are collected using interview, observation, test and instrument used is test items. In order to analyze the data students’ reading score-, percentage formula is used. Questioning Strategy improved the students’ reading comprehension in two cycles percentage of students scored ≥75 was 62,5% in the first cycle, and it was 81,25% in the second. Based on the research result, it can be concluded that Questioning Strategy is able to improve reading comprehension and students participation at SMA Muhammadiyah 2 Wuluhan in the 2015 – 2016 academic year.